Insulin-like growth factor-1 (IGF-1) is a compound produced through recombinant DNA technology. It serves as the main mediator for the growth-promoting effects of human growth hormone, thus also facilitating the growth of bones, muscles, and internal organs. Its impact on skeletal muscle is notably hyperplastic, leading to an increase in cell quantity. In contrast to human growth hormone, this substance exhibits potent insulin-like properties, supporting growth by enhancing the absorption of amino acids, glucose, and fatty acids, but it can lower blood sugar levels so effectively that an excessive dose may result in severe hypoglycemia.
Among the various anabolic effects that IGF-1 can induce in the body are enhancements in protein synthesis, improved nitrogen retention, and the stimulation of muscle fiber growth. These processes can take place when an adequate supply of amino acids (protein) is present. Research has shown that IGF-1 can assist in boosting collagen production and in regenerating cartilage within joints. Additionally, this hormone has demonstrated the potential to function as a neuroprotective agent and promoter, as IGF-1 receptors are found in brain tissue. Evidence suggests that supplementing with IGF-1 may slow the progression of certain brain diseases and help preserve brain function in some elderly individuals.
Regarding IGF-1 dosing, users have reported favorable outcomes with daily doses ranging from 100 to 160 mcg. This total amount is typically divided into several injections, most of which are likely administered following workouts.